- mgl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable group II metabotropic glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in nerve ring; neurons; and pharyngeal nervous system. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autistic disorder; and congenital stationary night blindness 1B. Is an ortholog of human GRM3 (glutamate metabotropic receptor 3).
- mgl-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in NSM; head neurons; and nerve ring. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autistic disorder; and congenital stationary night blindness 1B. Is an ortholog of human GRM8 (glutamate metabotropic receptor 8).
- mgl-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in several structures, including glutamatergic neurons; head neurons; pharyngeal nervous system; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Is an ortholog of human GRM1 (glutamate metabotropic receptor 1).
- C11E4.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in cytoplasm. Is an ortholog of human ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) and ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B).
- snt-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables calcium ion sensor activity and calcium-dependent phospholipid binding activity. Involved in several processes, including defecation; regulation of pharyngeal pumping; and synaptic vesicle endocytosis. Located in synaptic vesicle. Expressed in several structures, including excretory gland cell; gonad; nervous system; pharyngeal gland cell; and rectal gland cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1).
- F32B5.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B).