Predicted to enable molecular adaptor activity. Involved in several processes, including establishment of meiotic spindle localization; metaphase/anaphase transition of cell cycle; and polarity specification of anterior/posterior axis. Part of anaphase-promoting complex. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Is an ortholog of human ANAPC1 (anaphase promoting complex subunit 1).
Involved in asymmetric cell division; cortical granule exocytosis; and polarity specification of anterior/posterior axis. Predicted to be located in cytoplasm. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC27 (cell division cycle 27).
Predicted to enable molecular adaptor activity. Involved in asymmetric cell division; polarity specification of anterior/posterior axis; and positive regulation of metaphase/anaphase transition of meiosis I. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC23 (cell division cycle 23).
Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in asymmetric cell division; meiotic cell cycle; and polarity specification of anterior/posterior axis. Located in condensed chromosome and cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 109. Is an ortholog of human CDC20 (cell division cycle 20) and FZR1 (fizzy and cell division cycle 20 related 1).
Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in vulval development. Located in nucleus. Part of chromatin. Expressed widely. Is an ortholog of human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) and MBTD1 (mbt domain containing 1).