- kvs-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables voltage-gated potassium channel activity. Involved in several processes, including forward locomotion; hyperosmotic response; and mechanosensory behavior. Part of voltage-gated potassium channel complex. Expressed in PDA; amphid neurons; anal depressor muscle; sperm; and ventral cord neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1).
- mps-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; enteric muscle; intestine; lateral ganglion; and rectal muscle.
- mps-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in ADF; lumbar neurons; and pharyngeal neurons.
- mps-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables potassium channel regulator activity and protein serine/threonine kinase activity. Involved in several processes, including hyperosmotic response; mechanosensory behavior; and negative regulation of potassium ion transport. Located in axolemma; dendrite membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Expressed in amphid neurons; touch receptor neurons; and vulva.
- ssu-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables 1-hydroxypyrene sulfotransferase activity and aryl sulfotransferase activity. Involved in sulfur compound metabolic process. Located in cytosol. Expressed in ASJL and ASJR. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung non-small cell carcinoma (multiple); and reproductive organ cancer (multiple). Is an ortholog of several human genes including SULT1A1 (sulfotransferase family 1A member 1); SULT1A2 (sulfotransferase family 1A member 2); and SULT1E1 (sulfotransferase family 1E member 1).
- crt-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables calcium ion binding activity. Involved in several processes, including IRE1-mediated unfolded protein response; determination of adult lifespan; and hemidesmosome assembly. Located in cytoplasm. Expressed in several structures, including coelomocyte; excretory system; intestine; pharynx; and sperm. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human CALR (calreticulin).
- qua-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in molting cycle and nematode larval development. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in several structures, including P1; P12; P2; excretory system; and hypodermal cell.
- aff-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in regulation of egg-laying behavior and syncytium formation by plasma membrane fusion. Located in plasma membrane. Expressed in anchor cell; egg-laying apparatus; epithelial cell; neurons; and pharyngeal muscle cell.
- wrk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable axon guidance receptor activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules and synapse organization. Predicted to be located in axon; neuronal cell body; and plasma membrane. Expressed in several structures, including SMDVL; body ganglion; head neurons; hermaphrodite distal tip cell; and interfacial epithelial cell.