- unc-104 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cytoskeletal protein binding activity; phosphatidylinositol phosphate binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including chemical synaptic transmission; regulation of cellular component organization; and regulation of cellular localization. Located in axon; presynapse; and somatodendritic compartment. Expressed in epithelial cell; muscle cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and neuropathy (multiple). Is an ortholog of human KIF1A (kinesin family member 1A).
- klp-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in chromosome segregation. Located in neuronal cell body. Expressed in several structures, including ABa; EMS; Psub2; germ line; and head.
- klp-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15).
- klp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable microtubule binding activity. Involved in chromosome separation. Predicted to be located in microtubule cytoskeleton. Expressed in marginal cell. Is an ortholog of human KIFC3 (kinesin family member C3).
- klp-20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in ciliated neurons; distal tip cell; head; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in silicosis. Is an ortholog of human KIF3A (kinesin family member 3A).
- klp-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and microtubule-based movement. Located in axon; cytoplasmic microtubule; and neuronal cell body. Expressed in distal tip cell; dorsal nerve cord; head; and ventral nerve cord. Is an ortholog of human KIF13A (kinesin family member 13A) and KIF13B (kinesin family member 13B).
- klp-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic chromosome condensation and meiotic spindle midzone assembly. Located in condensed nuclear chromosome; nucleoplasm; and spindle. Expressed in germ line. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 100. Is an ortholog of human KIF4A (kinesin family member 4A).
- kap-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Contributes to microtubule motor activity. Involved in intraciliary anterograde transport; negative regulation of non-motile cilium assembly; and positive regulation of non-motile cilium assembly. Located in ciliary transition zone and non-motile cilium. Part of axonemal heterotrimeric kinesin-II complex. Expressed in ciliated neurons. Is an ortholog of human KIFAP3 (kinesin associated protein 3).