shk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables delayed rectifier potassium channel activity. Involved in potassium ion transmembrane transport. Located in plasma membrane. Expressed in body wall musculature; head ganglion; interneuron; muscle cell; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including developmental and epileptic encephalopathy 32; episodic ataxia type 1; and familial atrial fibrillation. Is an ortholog of several human genes including KCNA1 (potassium voltage-gated channel subfamily A member 1); KCNA2 (potassium voltage-gated channel subfamily A member 2); and KCNA3 (potassium voltage-gated channel subfamily A member 3).