Enables beta-N-acetylhexosaminidase activity. Involved in carbohydrate metabolic process. Predicted to be located in lysosome and membrane. Expressed in coelomocyte and pharyngeal neurons. Human ortholog(s) of this gene implicated in Sandhoff disease; Tay-Sachs disease; and spinal muscular atrophy. Is an ortholog of human HEXA (hexosaminidase subunit alpha) and HEXB (hexosaminidase subunit beta).
Enables hexosaminidase activity. Involved in carbohydrate metabolic process. Expressed in head muscle; tail; and vulva. Is an ortholog of human HEXD (hexosaminidase D).
Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Expressed in seam cell. Is an ortholog of human HEXD (hexosaminidase D).
Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Predicted to be located in membrane. Expressed in intestine. Is an ortholog of human HEXD (hexosaminidase D).
Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Expressed in head neurons; hypodermis; tail neurons; and vulva. Is an ortholog of human HEXD (hexosaminidase D).
Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Involved in IRE1-mediated unfolded protein response. Expressed in tail. Used to study Machado-Joseph disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12; obesity; and type 2 diabetes mellitus. Is an ortholog of human GFPT1 (glutamine--fructose-6-phosphate transaminase 1).