- gem-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in plasma membrane. Expressed in several structures, including hermaphrodite distal tip cell; neurons; pharynx; somatic gonad precursor; and vulval muscle.
- gem-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. Expressed in several structures, including Z2; Z3; head mesodermal cell; hermaphrodite gonad; and somatic gonad precursor. Is an ortholog of human CPNE5 (copine 5) and CPNE9 (copine family member 9).
- Y52B11A.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in congestive heart failure and type 2 diabetes mellitus. Is an ortholog of human REM1 (RRAD and GEM like GTPase 1); REM2 (RRAD and GEM like GTPase 2); and RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator).
- spv-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables GTPase activator activity. Involved in several processes, including cell-cell junction assembly; negative regulation of smooth muscle contraction; and regulation of protein localization. Located in apical plasma membrane and cell-cell junction. Expressed in head neurons; hypodermis; spermatheca; spermathecal cell; and tail neurons. Is an ortholog of human GMIP (GEM interacting protein).
- smi-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in embryo development. Located in cytoplasm. Expressed in body wall musculature; intestine; and ventral cord neurons. Used to study spinal muscular atrophy. Is an ortholog of human GEMIN2 (gem nuclear organelle associated protein 2).