- Zmpste24 [Search on AGR]
Homo sapiens This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
- fce-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables metalloendopeptidase activity. Involved in CAAX-box protein processing. Located in membrane. Expressed in head. Human ortholog(s) of this gene implicated in mandibuloacral dysplasia type B lipodystrophy and restrictive dermopathy 1. Is an ortholog of human ZMPSTE24 (zinc metallopeptidase STE24).
- frg [Search on AGR]
Mus musculus PHENOTYPE: Homozygotes have a short, wide face and small body size [provided by MGI curators]
- Crispld1 [Search on AGR]
Homo sapiens Involved in face morphogenesis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
- NALCN-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH congenital limbs-face contractures-hypotonia-developmental delay syndrome; genetic disease; Infantile Hypotonia with Psychomotor Retardation and Characteristic Facies 1; INTERACTS WITH 4,4'-sulfonyldiphenol; benzo[e]pyrene; bisphenol A
- F17C8.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective).
- crf30 [Search on AGR]
Mus musculus PHENOTYPE: A mutation in this unidentified gene results in a short snout and a wide face. [provided by MGI curators]
- crf29 [Search on AGR]
Mus musculus PHENOTYPE: A mutation in this unidentified gene results in a short, flattened snout and a wide face. [provided by MGI curators]
- Crispld2 [Search on AGR]
Homo sapiens Predicted to enable glycosaminoglycan binding activity. Involved in face morphogenesis. Located in transport vesicle. [provided by Alliance of Genome Resources, Apr 2022]
- Bey [Search on AGR]
Mus musculus PHENOTYPE: Homozygous lethal; heterozygotes are fertile, have a squat face and bulging eyes due to facial shortening and craniosynostosis. [provided by MGI curators]