- Y67A10A.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).
- exc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity. Involved in epithelial cell development and regulation of tube size. Predicted to be located in membrane. Expressed in amphid sheath cell and excretory canal.
- exc-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables single-stranded RNA binding activity. Involved in several processes, including epithelial cell development; regulation of alternative mRNA splicing, via spliceosome; and regulation of neuron differentiation. Located in nuclear speck. Expressed in several structures, including excretory cell; neurons; somatic nervous system; tail; and vulva. Is an ortholog of human ELAVL4 (ELAV like RNA binding protein 4).
- exc-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable zinc ion binding activity. Involved in anatomical structure morphogenesis; epithelial cell development; and regulation of tube size. Located in cytoplasm. Expressed in several structures, including ALM; distal tip cell; excretory canal; lumbar ganglion; and nerve ring. Is an ortholog of human CRIP1 (cysteine rich protein 1).
- F38E9.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is an ortholog of human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3).
- exc-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Involved in cell morphogenesis; epithelial cell development; and regulation of tube size. Located in several cellular components, including actin cytoskeleton; apical cortex; and cell body. Expressed in excretory cell; hermaphrodite gonad; neurons; pharyngeal muscle cell; and rectal epithelium. Used to study Charcot-Marie-Tooth disease type 4H and X-linked Aarskog syndrome. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 4H; X-linked Aarskog syndrome; and invasive ductal carcinoma. Is an ortholog of several human genes including FGD1 (FYVE, RhoGEF and PH domain containing 1); FGD3 (FYVE, RhoGEF and PH domain containing 3); and FGD4 (FYVE, RhoGEF and PH domain containing 4).
- exc-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chloride channel activity. Involved in epithelial cell development and regulation of tube size. Located in apical junction complex; apical plasma membrane; and lysosome. Expressed in several structures, including amphid sheath cell; excretory system; pharyngeal muscle cell; rectum; and vulva. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome and autosomal recessive nonsyndromic deafness 103. Is an ortholog of human CLIC2 (chloride intracellular channel 2) and CLIC4 (chloride intracellular channel 4).
- exl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chloride channel activity. Predicted to be involved in chloride transport. Located in apical plasma membrane; cytoplasm; and muscle cell projection membrane. Expressed in coelomocyte; intestine; muscle cell; and neurons. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome. Is an ortholog of human CLIC2 (chloride intracellular channel 2) and CLIC4 (chloride intracellular channel 4).