Expressed in excretory secretory system; intestine; muscle cell; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Human REPS1 enables SH3 domain binding activity. Is predicted to encode a protein with the following domains: EH domain; EF-hand domain pair; Phosphorylation site; and Cytoskeletal-regulatory complex EF hand. Is an ortholog of human REPS1 (RALBP1 associated Eps domain containing 1) and REPS2 (RALBP1 associated Eps domain containing 2).
Enables actin filament binding activity. Involved in several processes, including anatomical structure morphogenesis; barbed-end actin filament capping; and supramolecular fiber organization. Located in apical part of cell; brush border; and hemidesmosome. Expressed in several structures, including P3.pa; P3.pp; P5.ppp; P7.paa; and P9.p. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102; autosomal recessive nonsyndromic deafness 106; and hypotrichosis 5. Is an ortholog of human EPS8L1 (EPS8 signaling adaptor L1).