Enables voltage-gated calcium channel activity. Involved in several processes, including determination of left/right asymmetry in nervous system; positive regulation of striated muscle contraction; and regulation of pharyngeal pumping. Located in plasma membrane. Expressed in several structures, including alimentary muscle; neurons; preanal ganglion; tail; and vulval muscle. Used to study Duchenne muscular dystrophy and Timothy syndrome. Human ortholog(s) of this gene implicated in several diseases, including Brugada syndrome 3; X-linked recessive disease (multiple); and muscle tissue disease (multiple). Is an ortholog of human CACNA1C (calcium voltage-gated channel subunit alpha1 C); CACNA1F (calcium voltage-gated channel subunit alpha1 F); and CACNA1S (calcium voltage-gated channel subunit alpha1 S).
Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.
Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies.
Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus and nitroguanidine based on microarray studies.
Is affected by several genes including daf-12; eat-2; and eri-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine; fluoranthene; and paraquat based on microarray studies.
Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.