dna-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables 5'-3' DNA helicase activity; single-stranded DNA endodeoxyribonuclease activity; and single-stranded DNA helicase activity. Involved in DNA metabolic process. Located in nucleus. Expressed in gonad; oocyte; spermatheca; and uterus. Human ortholog(s) of this gene implicated in Seckel syndrome 8; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6; and isolated growth hormone deficiency type IA. Is an ortholog of human DNA2 (DNA replication helicase/nuclease 2).