Enables double-stranded DNA binding activity and enzyme binding activity. Involved in RNA processing and apoptotic DNA fragmentation. Part of exosome (RNase complex). Is an ortholog of human EXOSC5 (exosome component 5).
Enables nuclease activity and single-stranded DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Predicted to be located in cytoplasm. Is an ortholog of human ERI1 (exoribonuclease 1).
Enables flap endonuclease activity. Involved in apoptotic DNA fragmentation. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human FEN1 (flap structure-specific endonuclease 1).
Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (unc-13 homolog C).
Enables BH domain binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and positive regulation of apoptotic process.