Bma-ced-12.1

Brugia malayi

Enriched in digestive tract based on proteomic studies. Is predicted to encode a protein with the following domains: ELMO domain and ELMO/CED-12 family. Is an ortholog of C. elegans ced-12. In C. elegans, ced-12 is involved in several processes, including cytoskeleton organization; engulfment of apoptotic cell; and left/right axis specification.

Bma-ced-12.2

Brugia malayi

Is predicted to encode a protein with the following domains: ELMO domain; ELMO, armadillo-like helical domain; ELMO/CED-12 family; Engulfment and cell motility protein 3; Pleckstrin homology domain; and PH-like domain superfamily. Is an ortholog of C. elegans ced-12. In C. elegans, ced-12 is involved in several processes, including cytoskeleton organization; engulfment of apoptotic cell; and left/right axis specification.

Bma-ced-11

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is an ortholog of C. elegans ced-11. In C. elegans, ced-11 is involved in apoptotic process.

Bma-ced-8

Brugia malayi

Predicted to be located in membrane. Is an ortholog of C. elegans ced-8. In C. elegans, ced-8 is involved in apoptotic process; embryo development; and engulfment of apoptotic cell.

Bma-ced-4

Brugia malayi

Predicted to enable ADP binding activity. Is an ortholog of C. elegans ced-4. In C. elegans, ced-4 is involved in several processes, including muscle cell cellular homeostasis; positive regulation of synapse pruning; and regulation of apoptotic process.

Bm5640

Brugia malayi

Predicted to be involved in regulation of apoptotic process. Is an ortholog of O. volvulus Ovo-ced-9.

Bma-ced-1

Brugia malayi

Is predicted to encode a protein with the following domains: Laminin EGF domain; EGF-like domain; and Laminin-type EGF domain. Is an ortholog of C. elegans ced-1. In C. elegans, ced-1 is involved in several processes, including cytoskeleton organization; phagocytosis; and response to stress.

Bma-pat-12

Brugia malayi

Is an ortholog of C. elegans pat-12. In C. elegans, pat-12 is involved in embryonic morphogenesis and hemidesmosome assembly.

Bma-nlp-12

Brugia malayi

Is an ortholog of C. elegans nlp-12. In C. elegans, nlp-12 is involved in foraging behavior and neuropeptide signaling pathway.

Bma-ced-5

Brugia malayi

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Is an ortholog of C. elegans ced-5. In C. elegans, ced-5 is involved in several processes, including left/right axis specification; positive regulation of distal tip cell migration; and vesicle-mediated transport.