Enables GTPase activating protein binding activity. Involved in clathrin-dependent endocytosis; embryo development; and protein localization. Located in clathrin-coated endocytic vesicle and presynaptic periactive zone. Expressed in several structures, including anterior gonad arm; germ line; intestine; nervous system; and vulva. Is an ortholog of human AP2A1 (adaptor related protein complex 2 subunit alpha 1) and AP2A2 (adaptor related protein complex 2 subunit alpha 2).
Predicted to enable small GTPase binding activity. Involved in protein secretion. Predicted to be located in trans-Golgi network. Is an ortholog of human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1).
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Enables clathrin heavy chain binding activity and protein domain specific binding activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; egg-laying behavior; and positive regulation of growth rate. Located in cell cortex; clathrin-coated pit; and cytoplasmic vesicle. Expressed in several structures, including P5.ppp; amphid sheath cell; anchor cell; oocyte; and vulval cell. Human ortholog(s) of this gene implicated in autistic disorder and spinocerebellar ataxia type 37. Is an ortholog of human DAB1 (DAB adaptor protein 1).