aha-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; determination of adult lifespan; and social behavior. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in renal cell carcinoma and type 2 diabetes mellitus. Is an ortholog of human ARNT (aryl hydrocarbon receptor nuclear translocator) and ARNT2 (aryl hydrocarbon receptor nuclear translocator 2).