arx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and actin binding activity. Predicted to contribute to actin filament binding activity. Involved in Arp2/3 complex-mediated actin nucleation; embryonic morphogenesis; and epithelial cell migration. Located in cell leading edge and cytoplasm. Expressed in hypodermis. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glioblastoma; and opisthorchiasis. Is an ortholog of human ACTR3 (actin related protein 3).