lev-8

Caenorhabditis elegans

Is predicted to have acetylcholine-gated cation-selective channel activity and transmembrane signaling receptor activity. Is expressed in several structures, including DD neuron; anal depressor muscle; ganglia; head neurons; and uterine-vulval cell. Human ortholog(s) of this gene are implicated in autosomal dominant nocturnal frontal lobe epilepsy 3; congenital myasthenic syndrome (multiple); and multiple pterygium syndrome. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); and CHRNB4 (cholinergic receptor nicotinic beta 4 subunit).

acr-21

Caenorhabditis elegans

Is predicted to have acetylcholine-gated cation-selective channel activity and transmembrane signaling receptor activity. Is expressed in cholinergic neurons and ventral cord neurons. Is an ortholog of human CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit).

acr-8

Caenorhabditis elegans

Is predicted to have acetylcholine-gated cation-selective channel activity and transmembrane signaling receptor activity. Is expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene are implicated in autosomal dominant nocturnal frontal lobe epilepsy 3; congenital myasthenic syndrome (multiple); and multiple pterygium syndrome. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); and CHRNB4 (cholinergic receptor nicotinic beta 4 subunit).

acr-18

Caenorhabditis elegans

Is predicted to have extracellular ligand-gated ion channel activity and transmembrane signaling receptor activity. Is expressed in neurons and ray.

acr-12

Caenorhabditis elegans

Exhibits acetylcholine-gated cation-selective channel activity. Is involved in calcium ion import across plasma membrane and regulation of muscle contraction. Localizes to synapse. Is expressed in neurons. Human ortholog(s) of this gene are implicated in autosomal dominant nocturnal frontal lobe epilepsy 3; congenital myasthenic syndrome (multiple); and multiple pterygium syndrome. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); and CHRNB4 (cholinergic receptor nicotinic beta 4 subunit).

des-2

Caenorhabditis elegans

Is predicted to have extracellular ligand-gated ion channel activity and transmembrane signaling receptor activity. Localizes to integral component of plasma membrane. Is expressed in AIY; ALA; IL2 neuron; and pm1. Is an ortholog of human HTR3E (5-hydroxytryptamine receptor 3E).

acr-24

Caenorhabditis elegans

Is predicted to have extracellular ligand-gated ion channel activity and transmembrane signaling receptor activity.

acr-10

Caenorhabditis elegans

Is predicted to have acetylcholine-gated cation-selective channel activity and transmembrane signaling receptor activity. Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion).

T08G11.1

Caenorhabditis elegans

Is expressed in vulval muscle. Human ortholog(s) of this gene are implicated in Parkinson's disease 23 and choreaacanthocytosis. Is predicted to encode a protein with the following domains: Phosphorylation site; Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar sorting-associated protein 13, N-terminal; Repeating coiled region of VPS13; N-terminal region of Chorein or VPS13; SHR-binding domain of vacuolar-sorting associated protein 13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13, C-terminal; and Vacuolar protein sorting-associated protein 13, second N-terminal domain. Is an ortholog of human VPS13A (vacuolar protein sorting 13 homolog A).

zyg-13

Caenorhabditis elegans