zyg-12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dynein light intermediate chain binding activity and protein self-association. Involved in several processes, including centrosome localization; chromosome segregation; and pronuclear migration. Located in centrosome and nuclear envelope. Expressed in gonad and oocyte. Used to study Emery-Dreifuss muscular dystrophy. Is an ortholog of human HOOK1 (hook microtubule tethering protein 1) and HOOK2 (hook microtubule tethering protein 2).