sahd-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dGTPase activity; deoxynucleoside triphosphate hydrolase activity; and protein homodimerization activity. Involved in dGTP catabolic process. Predicted to be located in nucleus. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Chilblain lupus; and hepatitis B. Is an ortholog of human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1).