dve-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription activator activity, RNA polymerase II-specific; enzyme binding activity; and protein-folding chaperone binding activity. Involved in embryo development; mitochondrial unfolded protein response; and regulation of innate immune response. Located in cytosol and nucleus. Part of chromatin and transcription regulator complex. Expressed in several structures, including neurons; rectum; somatic nervous system; tail; and vulva. Human ortholog(s) of this gene implicated in SATB2-associated syndrome. Is an ortholog of human SATB1 (SATB homeobox 1) and SATB2 (SATB homeobox 2).