Enriched in several structures, including dopaminergic neurons; excretory cell;
mc2; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Sodium Chloride; and Rifampin based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Human CES1 enables carboxylesterase activity and sterol esterase activity. Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Carboxylesterase, type B; and Carboxylesterase family. Is an ortholog of human CES1 (carboxylesterase 1).