- gdi-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable Rab GDP-dissociation inhibitor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Down syndrome; non-syndromic X-linked intellectual disability 41; and psychotic disorder. Is an ortholog of human GDI1 (GDP dissociation inhibitor 1) and GDI2 (GDP dissociation inhibitor 2).
- vab-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity and structural molecule activity. Involved in epidermis morphogenesis. Located in apical plasma membrane; basal plasma membrane; and hemidesmosome. Expressed in several structures, including gonad; intestinal lumen; nerve ring; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex; hereditary sensory and autonomic neuropathy type 6; and lissencephaly 9 with complex brainstem malformation. Is an ortholog of human DST (dystonin).
- trmt-10A [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA N1-guanine methylation. Predicted to be located in nucleoplasm. Is an ortholog of human TRMT10A (tRNA methyltransferase 10A).
- Y57G11C.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).
- ccch-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2).
- nuo-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 33. Is an ortholog of human NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6).
- pde-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Expressed in AFDL and AFDR. Is an ortholog of human PDE10A (phosphodiesterase 10A).