Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including determination of adult lifespan; multivesicular body assembly; and positive regulation of vulval development. Predicted to be located in plasma membrane. Expressed in several structures, including excretory canal; germ line; tail; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Is an ortholog of human RALA (RAS like proto-oncogene A).
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process and leucine catabolic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).
Predicted to be involved in vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human AP3S1 (adaptor related protein complex 3 subunit sigma 1) and AP3S2 (adaptor related protein complex 3 subunit sigma 2).