Predicted to enable protein heterodimerization activity. Predicted to be involved in DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of epsilon DNA polymerase complex. Is an ortholog of human POLE4 (DNA polymerase epsilon 4, accessory subunit).
Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process and leucine catabolic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).