Predicted to enable DNA helicase activity and damaged DNA binding activity. Predicted to be involved in positive regulation of mitotic recombination and transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit).
Predicted to enable ATP binding activity; calmodulin binding activity; and phosphorylase kinase activity. Predicted to be involved in glycogen biosynthetic process and phosphorylation. Predicted to be part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXc and liver cirrhosis. Is an ortholog of human PHKG2 (phosphorylase kinase catalytic subunit gamma 2).