Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in mRNA transcription and mitotic cell cycle, embryonic. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIIK complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CDK7 (cyclin dependent kinase 7).
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process and leucine catabolic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).