Is an ortholog of several human genes including CTSE (cathepsin E); PGC (progastricsin); and REN (renin). Is predicted to have aspartic-type endopeptidase activity. Human ortholog(s) of this gene are implicated in familial juvenile hyperuricemic nephropathy.
Is an ortholog of human KMT2E (lysine methyltransferase 2E) and SETD5 (SET domain containing 5). Human ortholog(s) of this gene are implicated in autosomal dominant non-syndromic intellectual disability 23. Is predicted to encode a protein with the following domains: SET domain and SPK domain.