Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of several human genes including GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRB (glycine receptor beta).