- rabx-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endosomal vesicle fusion and molting cycle. Located in early endosome. Expressed in several structures, including coelomocyte; distal tip cell; neurons; ventral nerve cord; and vulva. Is an ortholog of human RABGEF1 (RAB guanine nucleotide exchange factor 1).
- cdc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic DNA replication checkpoint signaling. Located in condensed nuclear chromosome; cytoplasm; and nucleolus. Expressed in seam cell. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Is an ortholog of human CDC6 (cell division cycle 6).
- orc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to be involved in DNA replication initiation and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Is an ortholog of human ORC1 (origin recognition complex subunit 1).