Involved in macroautophagy and negative regulation of autophagosome assembly. Located in cytoplasm. Expressed in body wall musculature and pharyngeal muscle cell. Is an ortholog of human VMP1 (vacuole membrane protein 1).
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Part of nuclear pore. Is an ortholog of human NDC1 (NDC1 transmembrane nucleoporin).
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of several human genes including SLC22A11 (solute carrier family 22 member 11); SLC22A14 (solute carrier family 22 member 14); and SLC22A4 (solute carrier family 22 member 4).
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in acute kidney failure and rheumatoid arthritis. Is an ortholog of several human genes including SLC22A14 (solute carrier family 22 member 14); SLC22A2 (solute carrier family 22 member 2); and SLC22A4 (solute carrier family 22 member 4).
Enables propanoyl-CoA C-acyltransferase activity. Involved in several processes, including carbohydrate derivative metabolic process; dauer larval development; and positive regulation of developmental process. Located in peroxisome. Expressed in body wall musculature; hypodermis; intestine; and neurons. Used to study obesity. Human ortholog(s) of this gene implicated in Zellweger syndrome. Is an ortholog of human SCP2 (sterol carrier protein 2).