Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including mitochondrial unfolded protein response; mitochondrion organization; and nematode larval development. Located in mitochondrion. Expressed in hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; artery disease (multiple); and autoimmune disease of musculoskeletal system (multiple). Is an ortholog of human HSPD1 (heat shock protein family D (Hsp60) member 1).
Enables GTPase activating protein binding activity. Involved in molting cycle. Is an ortholog of human RABEP1 (rabaptin, RAB GTPase binding effector protein 1).
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate-mediated signaling. Expressed in pharyngeal muscle cell and rectal epithelium. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).
Predicted to enable inositol-polyphosphate 5-phosphatase activity. Involved in epidermal growth factor receptor signaling pathway; inositol phosphate-mediated signaling; and ovulation. Expressed in spermatheca. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A).
Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in neurons.
Enables identical protein binding activity. Involved in centrosome cycle; positive regulation of mitotic cell cycle, embryonic; and protein localization to organelle. Located in centrosome and cytoplasm.