ttx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of plasma membrane bounded cell projection assembly; thermosensory behavior; and transcription by RNA polymerase II. Located in nucleus. Expressed in head neurons and pharyngeal cell. Human ortholog(s) of this gene implicated in panhypopituitarism and syndromic microphthalmia 5. Is an ortholog of human OTX1 (orthodenticle homeobox 1).