Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Is an ortholog of human GTF2A2 (general transcription factor IIA subunit 2).
Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (unc-13 homolog C).
Enables BH domain binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and positive regulation of apoptotic process.