Is affected by several genes including daf-2; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies.
Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2).
Is affected by several genes including daf-2; eat-2; and elt-2 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and enzyme inhibitor activity. Involved in several processes, including defense response to other organism; determination of adult lifespan; and nematode larval development. Located in nucleus. Expressed in several structures, including AWC; Ealaa; Ealp; Earaa; and intestine. Human ortholog(s) of this gene implicated in several diseases, including adenocarcinoma (multiple); artery disease (multiple); and congenital heart disease (multiple). Is an ortholog of human GATA4 (GATA binding protein 4); GATA5 (GATA binding protein 5); and GATA6 (GATA binding protein 6).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate determination. Located in nucleus. Expressed in E lineage cell.
Is affected by several genes including daf-2; elt-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by seven chemicals including tryptophan; allantoin; and Sirolimus based on microarray and RNA-seq studies.
Is affected by rsr-2; mir-34; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4.
Is affected by several genes including eat-2; elt-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.