Enables DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of locomotion and response to xenobiotic stimulus. Predicted to be located in nucleus. Predicted to be part of nuclear aryl hydrocarbon receptor complex. Expressed in ALML; ALMR; RMEL; RMER; and neurons. Human ortholog(s) of this gene implicated in pancreatic cancer and retinitis pigmentosa 85. Is an ortholog of human AHR (aryl hydrocarbon receptor).
Is affected by several genes including cep-1; egl-9; and ahr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies.
Is affected by several genes including smg-2; ahr-1; and etr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
Is affected by several genes including lem-2; ahr-1; and emr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Ethanol; sodium arsenite; and bisphenol A based on RNA-seq studies.
Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans ahr-1. In C. elegans, ahr-1 is involved in negative regulation of locomotion and response to xenobiotic stimulus.
Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans ahr-1. In C. elegans, ahr-1 is involved in negative regulation of locomotion and response to xenobiotic stimulus.