Is affected by several genes including mdt-15; met-2; and spr-5 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies.
Involved in lateral inhibition; positive regulation of Notch signaling pathway; and regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in body wall musculature.
Is affected by several genes including sir-2.1; mdt-15; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies.
Enables nuclear receptor binding activity and transcription coactivator activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and sequestering of triglyceride. Predicted to be located in nucleus. Expressed in head. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MED15 (mediator complex subunit 15).
Is affected by several genes including eat-2; mdt-15; and atfs-1 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.