- Mpv17 [Search on AGR]
Homo sapiens This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). [provided by RefSeq, Jul 2008]
- cps-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrion. Is an ortholog of human ENDOG (endonuclease G).
- Myk103 [Search on AGR]
Mus musculus PHENOTYPE: This locus is the integration site of a transgene containing Mt1 and functional HSV thymidine kinase that causes sperm infertility when expressed postmeiotically. Transmission of the transgene-bearing chromosome is normal in females, but it is not transmitted by males unless the transgene been lost. [provided by MGI curators]
- rrf-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA-dependent RNA polymerase activity. Involved in regulatory ncRNA-mediated heterochromatin formation and spermatogenesis. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Expressed in head and tail.
- adr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables mRNA binding activity. Involved in several processes, including adenosine to inosine editing; determination of adult lifespan; and regulation of vulval development. Located in cytosolic ribosome and nucleus. Expressed in body wall musculature; intestine; nervous system; and vulva.
- hel-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in determination of adult lifespan; nuclear mRNA surveillance; and positive regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Expressed in hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is an ortholog of human DDX39A (DExD-box helicase 39A).
- mut-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity and RNA helicase activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in mutator focus. Expressed in germ cell and germ line.