deg-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ligand-gated sodium channel activity. Involved in response to acidic pH and response to amino acid. Predicted to be located in membrane. Expressed in AVG; IL1 neuron; anal depressor muscle; body wall musculature; and command interneuron. Used to study hypokalemic periodic paralysis and neurodegenerative disease. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma).