t [Search on AGR]
Mus musculus PHENOTYPE: Mice carrying a t haplotype and heterozygous for a dominant brachyury allele are tailless. Mice inheriting specific combinations of t haplotypes may show transmission ratio distortion, recombination suppression, male sterility, or lethality. [provided by MGI curators]
t [Search on AGR]
Drosophila melanogaster tan (t) encodes a hydrolase involved in both the conversion of N-beta-alanyldopamine to dopamine in the cuticle and central nervous system, and the conversion of beta-alanylhistamine (carcinine) to histamine in the retina. It functions in vision, cuticular melanization, and neurotransmitter recycling.
Tbxt [Search on AGR]
Homo sapiens The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]