adr-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables double-stranded RNA adenosine deaminase activity. Involved in adenosine to inosine editing; determination of adult lifespan; and positive regulation of chemotaxis. Located in cytoplasm and nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; and dyschromatosis symmetrica hereditaria. Is an ortholog of human ADARB1 (adenosine deaminase RNA specific B1).