mbk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including anterior gonad arm. Used to study Down syndrome and intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; abdominal obesity-metabolic syndrome 3; and autosomal dominant intellectual developmental disorder 7. Is an ortholog of human DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A).