- sm [Search on AGR]
Drosophila melanogaster smooth (sm) encodes an RNA binding, heterogeneous nuclear ribonucleoprotein involved in axon guidance, mRNA processing, chemosensation, determination of lifespan and feeding behavior.
- sms-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane.
- sms-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane.
- sms-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in Golgi membrane. Expressed in head muscle; pharyngeal cell; rectal muscle; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Is an ortholog of human SGMS2 (sphingomyelin synthase 2).
- sms-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane. Expressed in marginal cell; pharyngeal muscle cell; pharynx; and spermatheca.
- Sms [Search on AGR]
Mus musculus PHENOTYPE: Male mice hemizygous for a knock-out allele exhibit muscle weakness, decreased lean body mass and bone mineral density, lumbar lordosis, postnatal growth retardation, and male infertility. [provided by MGI curators]
- Sms [Search on AGR]
Homo sapiens This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
- Sms [Search on AGR]
Rattus norvegicus Enables spermine synthase activity. Involved in spermine biosynthetic process. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Snyder type. Orthologous to human SMS (spermine synthase); PARTICIPATES IN spermine metabolic pathway; methionine cycle/metabolic pathway; polyamine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.