Enables several functions, including LIM domain binding activity; kinase binding activity; and protein-macromolecule adaptor activity. Involved in dephosphorylation and regulation of egg-laying behavior. Located in I band and M band. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human CTDSP1 (CTD small phosphatase 1) and CTDSPL (CTD small phosphatase like).
Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Is an ortholog of human TIMM50 (translocase of inner mitochondrial membrane 50).
Predicted to enable protein serine/threonine phosphatase activity. Involved in nuclear membrane reassembly and regulation of nuclear division. Located in nuclear envelope. Is an ortholog of human CTDNEP1 (CTD nuclear envelope phosphatase 1).
Involved in regulation of nuclear division. Predicted to be located in cytoplasm and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Is an ortholog of human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1).
Enables MATH domain binding activity; enzyme binding activity; and guanyl-nucleotide exchange factor activity. Involved in several processes, including myofibril assembly; pharyngeal gland morphogenesis; and regulation of striated muscle contraction. Located in M band. Expressed in alimentary muscle; gonad; tail; and vulval muscle. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Is an ortholog of human SPEG (striated muscle enriched protein kinase).
Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Involved in several processes, including endomembrane system organization; macromolecule localization; and nematode larval development. Located in endoplasmic reticulum; nuclear envelope; and nucleoplasm. Expressed in head neurons and hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in morbid obesity. Is an ortholog of human LPIN2 (lipin 2).