Involved in lysosome organization. Predicted to be located in endosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 6. Is an ortholog of human PLEKHM1 (pleckstrin homology and RUN domain containing M1).
Is predicted to encode a protein with the following domains: RUN domain; SH3-like domain superfamily; SH3 domain; RUN domain superfamily; and Homeobox-like domain superfamily.
Enables small GTPase binding activity. Involved in several processes, including dense core granule maturation; positive regulation of behavior; and regulation of transport. Located in several cellular components, including Golgi trans cisterna; neuronal cell body; and perinuclear region of cytoplasm. Expressed in uterus. Is an ortholog of human RUNDC1 (RUN domain containing 1).
Is predicted to encode a protein with the following domains: RUN domain superfamily; PDZ superfamily; RUN domain; and PDZ domain. Is an ortholog of C. elegans nrfl-1.
Is predicted to encode a protein with the following domains: PH-like domain superfamily; Phosphotyrosine interaction domain (PTB/PID); RUN domain; RUN domain superfamily; PTB/PI domain; and PDZ superfamily.
Enables protein kinase binding activity and scaffold protein binding activity. Involved in regulation of protein localization and synaptic vesicle localization. Located in neuron projection. Expressed in several structures, including hypodermis; intestine; motor neurons; muscle cell; and uterus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 61. Is an ortholog of human RUSC1 (RUN and SH3 domain containing 1) and RUSC2 (RUN and SH3 domain containing 2).
Is predicted to encode a protein with the following domains: RUN domain superfamily and RUN domain. Is an ortholog of C. elegans cup-14. In C. elegans, cup-14 is involved in lysosome organization.