ztf-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in accessory cell; gonad; hypodermis; and tail. Human ortholog(s) of this gene implicated in several diseases, including B-lymphoblastic leukemia/lymphoma; carcinoma (multiple); and common variable immunodeficiency 13. Is an ortholog of several human genes including IKZF1 (IKAROS family zinc finger 1); IKZF2 (IKAROS family zinc finger 2); and IKZF3 (IKAROS family zinc finger 3).