Enables protein tyrosine phosphatase activity. Involved in several processes, including embryonic morphogenesis; nervous system development; and neuroblast migration. Located in adherens junction and synapse. Expressed in embryonic cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in hyperinsulinism and obesity. Is an ortholog of human PTPRD (protein tyrosine phosphatase receptor type D) and PTPRF (protein tyrosine phosphatase receptor type F).
Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).
Predicted to enable non-membrane spanning protein tyrosine phosphatase activity and phosphotyrosine residue binding activity. Involved in several processes, including nematode larval development; positive regulation of signal transduction; and positive regulation of vulval development. Located in cytoplasmic vesicle. Expressed in body wall musculature; head ganglion; pharynx; spermatheca; and tail. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 1; Noonan syndrome with multiple lentigines 1; and anogenital venereal wart. Is an ortholog of human PTPN6 (protein tyrosine phosphatase non-receptor type 6).
Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human PRELID3B (PRELI domain containing 3B).
Predicted to enable protein tyrosine phosphatase activity. Located in sarcoplasmic reticulum. Expressed in muscle cell; nerve ring; neurons; pharyngeal nervous system; and ventral nerve cord. Is an ortholog of human PTPN3 (protein tyrosine phosphatase non-receptor type 3) and PTPN4 (protein tyrosine phosphatase non-receptor type 4).
Is predicted to encode a protein with the following domain: Protein-tyrosine phosphatase-like. Is an ortholog of C. elegans ptp-5.1; ptp-5.2; and ptp-5.3.
Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP. Is an ortholog of human SF3B3 (splicing factor 3b subunit 3).
Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is an ortholog of human SF3B6 (splicing factor 3b subunit 6).