Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is an ortholog of human SLC22A15 (solute carrier family 22 member 15).
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Enables organic cation transmembrane transporter activity. Involved in determination of adult lifespan and organic cation transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including myelodysplastic syndrome; rheumatoid arthritis; and systemic primary carnitine deficiency disease. Is an ortholog of human SLC22A4 (solute carrier family 22 member 4).