LINC00630

Homo sapiens

ASSOCIATED WITH Autism; autistic disorder; deafness-intellectual disability, Martin-Probst type syndrome; INTERACTS WITH acrylamide; aflatoxin B1; phenylmercury acetate

scl-21

Caenorhabditis elegans

Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C).

C35D10.17

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of human CMC2 (C-X9-C motif containing 2).

npr-20

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CCR1 (C-C motif chemokine receptor 1); CCR3 (C-C motif chemokine receptor 3); and CXCR5 (C-X-C motif chemokine receptor 5).

cchl-1

Caenorhabditis elegans

Predicted to enable holocytochrome-c synthase activity. Predicted to be involved in cytochrome c-heme linkage. Located in mitochondrion. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 1 and microphthalmia. Is an ortholog of human HCCS (holocytochrome c synthase).

plc-2

Caenorhabditis elegans

Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol-mediated signaling.

cox-4

Caenorhabditis elegans

Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2).

coa-3

Caenorhabditis elegans

Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COA3 (cytochrome c oxidase assembly factor 3).

F01F1.2

Caenorhabditis elegans

Predicted to be located in mitochondrion. Expressed in body wall musculature; intestine; and pharyngeal muscle cell. Is an ortholog of human CMC1 (C-X9-C motif containing 1).

coa-5

Caenorhabditis elegans

Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 3. Is an ortholog of human COA5 (cytochrome c oxidase assembly factor 5).