Expressed in anterior hypodermis; hyp7 syncytium; and tail hypodermis. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily.
Expressed in rectal epithelium; seam cell; and vulval cell. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily.
Predicted to enable clathrin adaptor activity. Involved in apical protein localization and protein secretion. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of AP-1 adaptor complex. Is an ortholog of human AP1G1 (adaptor related protein complex 1 subunit gamma 1).
Predicted to be involved in intracellular transport and synaptic vesicle membrane organization. Predicted to be located in endosome membrane; presynaptic endosome; and terminal bouton. Predicted to be part of AP-3 adaptor complex. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome. Is an ortholog of human AP3D1 (adaptor related protein complex 3 subunit delta 1).
Predicted to enable metal ion binding activity. Expressed in several structures, including Z4.ap; dorsal uterine precursor; head muscle; head neurons; and ventral uterine precursor. Is an ortholog of human ZNF501 (zinc finger protein 501).
Predicted to enable clathrin binding activity. Predicted to be involved in intracellular transport. Predicted to be located in trans-Golgi network membrane. Predicted to be part of AP-1 adaptor complex. Is an ortholog of human AFTPH (aftiphilin).
Involved in apical protein localization. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of AP-1 adaptor complex. Human ortholog(s) of this gene implicated in MEDNIK syndrome; psoriasis 15; and syndromic X-linked intellectual disability 5. Is an ortholog of human AP1S1 (adaptor related protein complex 1 subunit sigma 1) and AP1S2 (adaptor related protein complex 1 subunit sigma 2).
Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex
Enables 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity and bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. Involved in nucleotide metabolic process. Is an ortholog of human NUDT2 (nudix hydrolase 2).
Small subunit of the clathrin-associated adaptor complex AP-2; AP-2 is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex